Iran and the S-300

Israel: Iran may share S-300 missiles with Hizballah and Syria

US Secretary of State John Kerry protested that the S-300 in Iranian hands could endanger America’s allies in the Middle East. Russian Foreign Minister, Sergei Lavrov replied that the missile was a defensive system rather than a weapon of attack, and it therefore threatened no one, certainly not Israel.

S-300s have a range of 200 km. Source: Jerusalem Post

Yes, but how do you take out their nuclear facilities, if need be, once the S-300s are in place?